So long, farewell….

BrandnB: Okay guys, farewell till next time meaning a month or two till our next post… Ok you caught us… We will be back soon to share our understanding in the subject of Biochemistry. BrandnB here yet again expressing my thanks for the new followers, viewers, especially the viewers from other countries and also my fellow bloggers you know yourselves once again thanks till next time.

Hazel-Ann: Well guys this brings us to the end of blogging for this semester (don’t worry we’ll be back :P)! I must say the journey has just begun and so far it has been quite prosperous and I am honoured to have worked alongside all of the other members of Twisteddnas: Breaking the Bond! I have learned from this blogging activity that great team work is an important asset to a holistic individual. Constant blogging has also helped me in remembering what was taught by my amazing lecturer, Mr. Jason Matthew. Through this activity I was able to express my thoughts about Biochemistry thus far. I have also seen a great improvement in my creativity skills and have become more of an innovative thinker because of this blogging. I have learnt skills I have never been exposed to before like how to do a wordle, a video review, a reflection, even how to blog and much more! I am grateful for the experience and surely look forward to moving on to year two of Biochemistry and to embrace what it has to offer. I hope that Twisteddnas: Breaking the Bond has been helpful to you in many ways. So goodbye for now and I wish all of my colleagues good luck in final exams!

Kevin: Hello friends. This is Kevin here. It’s been a long and hard semester and we have finally completed our creative and helpful blog. This is definitely not a goodbye note but it’s simply a conclusion of all our work during this semester. I had absolute fun with this blog because it was a new, creative form of learning, not for just me but also for all our viewers and the other member of Twisted DNAs. I’d also like to thank our lecturer Mr. Jason Matthew for his guidance and effective teaching abilities. Additionally, I know I speak for everyone when I say that we all enjoyed making this blog and we hope you guys enjoy it as well. See you guys!!

Aaliyah: Hey guys! Well this semester has finally come to an end and that means blogging is over. *sad face* It definitely was an enjoyable experience, hard at times, but fun and helpful anyway. Continue to be the amazing Biochemians you are and work hard towards your goal! Thank you all for viewing our blog and I hope that it helped in some way J Farewell for now, wishing my peers (and myself lol) all the best in finals!

Kim: Hey guys its Kim. It has been great over the past few months blogging about biochemistry. I have learnt a lot while teaching the world biochemistry. Hopefully this is not the last time you guys hear from us. Certainly I have enjoyed blogging and so much so I have decided to take it up as a hobby of mine. Thanks guys for reading our blog and wish us luck for finals, they are in a couple weeks!

 

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FUN FACTS ABOUT ENZYMES

E– Enzymes are very specific. Some enzymes only catalyze one specific reaction, while others only act on a particular functional group, chemical bond or optical isomer.

N Not all enzymes are proteins. Shocking, I know! Some RNA molecules actually act as enzymes and these are called ribozymes, and also, some antibodies have catalytic properties, and these are called abzymes.

Z(I couldn’t think of anything with Z so an exclamation from Shaggy in Scooby Doo will have to suffice lol) Did you know that all metabolic reactions in the cell are catalyzed by enzymes? The reactions are too slow to occur on their own, so we would all be dead if there weren’t enzymes in our body!

Y-Yeast enzymes are used in fermentation. These enzymes break down disaccharides to simple sugars, and in the process, alcohol and carbon dioxide is produced. This fermentation process is what allows us to get wine from fruit juices and beer from wort. So for all of you wine and beer lovers out there know that you get your favourite drinks via the actions of enzymes.

M-Meeting of enzymes and substrates occur at a point on the enzyme called the active site. The enzyme gets near the substrate and is all like   (lol) and since enzymes are proteins, the amino acid residues of the active site binds with the substrate through interactions like hydrophobic interactions, electrostatic interactions, hydrogen bonding and Van der Waals interactions.

E– Every woman takes a pregnancy test at least once in her life, I assume. But did you know that pregnancy tests work via the action of enzymes as well? The hormone human chorionic gonadotropin (HCG) is produced after a woman becomes pregnant. The HCG in her urine, reacts with an antibody-enzyme complex, forming an HCG-antibody enzyme complex confirming her pregnancy.

And just for a little enzyme joke : 

References:

Worthington Biochemical Corporation. “Introduction to Enzymes.” Specificity of Enzymes. http://www.worthington-biochem.com/introbiochem/specificity.html (accessed March 2, 2014).

“ELISA for Home Pregnancy Test.”http://www.elisa-antibody.com/ELISA-applications/home-pregnancy-test (accessed March 2, 2014).

HowStuffWorks.com. “Yeast.” HowStuffWorks. http://science.howstuffworks.com/life/fungi/yeast-info.htm (accessed March 3, 2014).

ALL ABOUT ENZYMES

Hey guys, Aaliyah here and this week we’re talking about enzymes. 🙂 Now, I particularly love this topic so I hope you guys enjoy learning new things about enzymes with me.

Spongebob - ENZYMES

Most enzymes are proteins . Enzymes are biological catalysts that speed up the rate of a chemical reaction but remain unchanged during the reaction.

The way enzymes work is by lowering the activation energy of a reaction so the reaction occurs more easily and faster. The activation energy is simply the minimum energy required for a reaction to occur, either substances reacting together, or a substance being broken down. The graph below shows how this happens.

To help understand, you can imagine that a car going over a hill is the reaction you want to occur. The uncatalyzed reaction requires a lot of energy from the car, since the hill is high. You’re going to be mashing X like crazy! The enzyme steps in and cuts down the hill for you, making it a shorter hill to go over. This would be the enzyme lowering the activation energy, and the car can go over the hill while using less energy and power. The car both starts and ends at the same places in both “reactions”, but the energy required to get the car over the tall hill is much more than the energy required going over the short hill.

Now, one thing that I surely didn’t know before was that enzymes are classified into six groups. It’s preferred that you learn them in a specific order so I’ve come up with this to help me remember and I hope it helps you too-using the first letters of these words Only The Happy Life Is Lovely. Corny, I know lol…but it helps! These stand for Oxidoreductases, Transferases, Hydrolases, Lyases , Isomerases and Ligases, all of which catalyze different types of reactions.

There are two theories as to how enzymes work- The Lock and Key Theory and The Induced Fit Theory.

In the lock and key theory, the shape of the active site is complementary to the shape of the substrate.  The lock is analogous to the enzyme and the key is analogous to the substrate. The correct key would fit into the key hole of the lock, just like the correct substrate would fit into the correct active site of the enzyme, as shown in the illustration below.

In the Induced Fit Theory the substrate can slightly alter the shape of the active site in the enzyme so that it can fit, as shown in the illustration below.

Now there are many more things I can say about enzymes, but I don’t want to keep rambling for too long, so the last thing I’ll leave you with is a basic summary on how enzymes work in a reaction.

Enzyme + Substrate ==> enzyme-substrate complex ==> Enzyme + Products

And there you have it! Hope you guys enjoyed this post, and I hope you learnt at LEAST one thing. Be sure to check out the following post for some interesting facts about enzymes and look out for a cool word cloud on all things enzymes! 🙂 Now, if only there was an enzyme to help us study faster, like Studyase…sighhh!

Until next time!    

References:

Nelson, David L., and Michael M. Cox. 2008. Lenhinger Principles of Biochemistry. 5th edition. New York: W.H Freeman and Company.

“Mechanism of Enzyme Action.” Enzymes. http://www.elmhurst.edu/~chm/vchembook/571lockkey.html (accessed March 2, 2014).